Breakthrough In Blocking Malaria Transmission

A team of researchers may have found a way to stop the transmission of malaria which will significantly prevent the spread of one of the deadliest diseases out there at the moment.

By disrupting the potassium channel of the malaria parasite, a team of researchers has been able to prevent new malaria parasites from forming in mosquitoes and has thereby broken the cycle of infection during recent animal tests.

By genetically altering the malaria parasite through gene knock-out technol-ogy, a research team consisting of scientists at the University of Copenha-gen and John Hopkins University, Baltimore, has prevented the parasite from going through the normal stages of its life cycle and developing a cyst (egg-like structure or occyst), which spawns new infectious parasites." As it is exclusively the parasites from these oocysts that can infect new individu-als, we were able to prevent the disease from being transmitted to the animals in our tests", explains Assistant Professor, Peter Ellekvist from the University of Copenhagen.

The findings have been published in the scientific journal Proceedings of the National Academy of Sciences, USA, (2008 105: 6398-6402).



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